My current research aims to understand the effects of specific errors in DNA, and ultimately determine if they affect the response of an individual cancer patient to therapy. I am particularly interested in precision medicine for cancer patients. My current projects are integrating molecular biology, “big data”, and translational patient xenografting techniques to develop a method for selecting patients who will benefit from an existing anti-cancer agent. Some of my other interests include:
- Examining molecular cross-talk between signaling pathways.
- Exploring epigenetic regulation of genes throughout mammary development.
- Optimizing models to mimic human cancers in vitro and in vivo.
To view my CV, you can click here: Krysta Mila Coyle .